Ubiquitin and the Biology of the Cell

Hardcover | May 31, 1998

EditorJan-Michael Peters, J. Robin Harris, Daniel Finley

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Research Institute of Molecular Pathology, Vienna, Austria. Text addressing the importance of ubiquitin-dependent proteolysis as a regulatory mechanism. Recounts the work that led to this new perception. For researchers and students in the field of cell biology, signal transduction, protein sorting, neuropathology, oncology, and virology. Modified-outline format.

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Research Institute of Molecular Pathology, Vienna, Austria. Text addressing the importance of ubiquitin-dependent proteolysis as a regulatory mechanism. Recounts the work that led to this new perception. For researchers and students in the field of cell biology, signal transduction, protein sorting, neuropathology, oncology, and virolo...

Format:HardcoverDimensions:494 pages, 9.21 × 6.14 × 0.27 inPublished:May 31, 1998Publisher:Springer US

The following ISBNs are associated with this title:

ISBN - 10:0306456494

ISBN - 13:9780306456497

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Table of Contents

The Ubiquitin System: Past, Present and Future Perspectives; A. Hershko. Polyubiquitin Chains; C.M. Pickart. The Ibiquitin-Conjugation System; M. Scheffner. The Deubiquitinating Enzymes; K.D. Wilkinson, M. Hochstrasser. The 20S Proteasome; A. Lupas, W. Baumeister. The 26S Proteasome; M. Rechsteiner. Function of the Proteasome in Antigen Presentation; J. Beninga, A.L. Goldberg. The N-end Rule Pathway; A. Varshavsky, et al. Ubiquitin-Dependent Degradation of Transcriptional Regulators; M. Hochstrasser, D. Kornitzer.. Role of the Ubiquitin-Proteasome Pathwayi in Nf-KB Activation; Z.J. Chen, T. Maniatis. Ubiquitination of the 053 Tumor Suppressor; J.M. Huibregtse, et al. Ubiquitination of Integral Membrane Proteins and Proteins in the Secretory Pathway; R.R. Kopito. Degradation of Ornithine Decarboxylase; P. Coffino. Ubiquitin and the Molecular Pathology of Human Disease; R.J. Mayer, et al. Index.