Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression by Lucy W. BarrettUntranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression by Lucy W. Barrett

Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression

byLucy W. Barrett, Sue Fletcher, Steve D. Wilton

Paperback | July 9, 2013

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There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
Title:Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene ExpressionFormat:PaperbackDimensions:56 pagesPublished:July 9, 2013Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3034806787

ISBN - 13:9783034806787

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Table of Contents

Introduction.- Promoter.- 5' Untranslated Region.- Structure.- Intronic Regions.- 3' Untranslated Region.- Non-coding RNAs.- Conclusion.