Vaccines for Pandemic Influenza by Richard W CompansVaccines for Pandemic Influenza by Richard W Compans

Vaccines for Pandemic Influenza

EditorRichard W Compans, Walter A. Orenstein

Paperback | November 29, 2011

Pricing and Purchase Info

$317.61 online 
$363.95 list price save 12%
Earn 1,588 plum® points

Prices and offers may vary in store


In stock online

Ships free on orders over $25

Not available in stores


The recent outbreak of disease caused by a novel H1N1 virus has focused global attention on the threat of a new influenza pandemic. Recent years have also seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans resulting in numerous fatalities. The rapid expansion in the geographic distribution of these novel viruses raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have limited antigenic relationships to the newly emerging virus strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop effective vaccines for pandemic influenza viruses, and to overcome the limitations inherent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine production; which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations... more on
Title:Vaccines for Pandemic InfluenzaFormat:PaperbackDimensions:530 pages, 9.25 × 6.1 × 0 inPublished:November 29, 2011Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3642242405

ISBN - 13:9783642242403

Look for similar items by category:


Table of Contents

Preface.- Pandemic influenza as a current threat.- Designing vaccines for pandemic influenza.- Current vaccines for seasonal influenza.- Generation and characterization of candidate vaccine viruses for pre-pandemic influenza vaccines.- Recombinant proteins produced in insect cells.- Adjuvants for pandemic influenza vaccines.- Live attenuated vaccines for pandemic influenza.- Influenza vaccines for avian species.- Development and application of avian influenza vaccines in China.- Attenuated influenza virus vaccines with modified NS1 proteins.- DNA Vaccines against Influenza viruses.- Influenza neuraminidase as a vaccine antigen.- Recombinant vectors as influenza vaccines.- Universal Pandemic Influenza Vaccines.- Influenza virus-like particles as pandemic vaccines.- Antigenic cross-reactivity among H5N1 viruses.- Transcutaneous immunization with influenza vaccines.- Self-administered microneedle patches for pandemic influenza.- Animal models for evaluation of influenza vaccines.- Immunosenescence and influenza vaccine efficacy.- Summary of recent clinical trials.- Considerations for licensure of pandemic and pre-pandemic indications in the U.S..- Strategies for Broad Global Access to Pandemic Influenza Vaccines.- Prioritization of Pandemic Influenza Vaccine: Rationale and Strategy for Decision-Making.- Subject index.