Vaccines for the Prevention of Cervical Cancer

Paperback | December 19, 2009

byPeter L. Stern, Henry C. Kitchener

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Cervical cancer is the second most common form of cancer found in women and it is responsible for more than a quarter of a million deaths worldwide each year. With approximately 70% of cervical cancers now known to be caused by two types of the human papilloma virus (HPV), there is greatinterest surrounding the approval of the first preventative vaccines for clinical use. Despite this excitement, many questions remain about how the new vaccines should best be implemented and how cervical cancer screening will change following vaccination.Part of the Oxford Oncology Library series, this practical pocketbook provides an overview of the role of HPV in the pathology of cervical cancer and its current screening and management, the principles of immune control of HPV infection in cervical cancer, and the challenges of implementing HPVvaccines and future developments.

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Cervical cancer is the second most common form of cancer found in women and it is responsible for more than a quarter of a million deaths worldwide each year. With approximately 70% of cervical cancers now known to be caused by two types of the human papilloma virus (HPV), there is greatinterest surrounding the approval of the first pr...

Peter L. Stern is Professor of Immunology at the Paterson Institute for Cancer Research, University of Manchester, Manchester, UK. Henry C. Kitchener is Professor of Gynaecological Oncology at St Mary's Hospital, University of Manchester, Manchester, UK.

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Format:PaperbackDimensions:176 pages, 7.09 × 3.94 × 0.07 inPublished:December 19, 2009Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199588635

ISBN - 13:9780199588633

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Table of Contents

Part 1: Prevention and current treatment1. Karin Denton: The UK cervical screening programme2. Julia E. Palmer and John A. Tidy: Management of Cervical Intraepithelial Neoplasia (CIN)Part 2: HPV and disease3. Sally Roberts and Lawrence S. Young: Role of HPV in cervical carcinogenesis4. F. Xavier Bosch, Silvia de Sanjose, and Xavier Castallsague: HPV and genital cancer: the essential epidemiology5. Margaret E. Cruickshank: The role of HPV testing in cervical screeningPart 3: Immune control of HPV infection in cervical neoplasia6. Peter L. Stern: Natural immune control of HPV infection7. Margaret A. Stanley: Prophylactic HPV vaccines: pre-clinical and proof of principle studies8. Henry C. Kitchener: Prophylactic HPV vaccination: current status9. Loretta Brabin: Introduction of HPV prophylactic vaccinationPart 4: Challenges and future developments10. Rengaswamy Sankaranarayanan and Catherine Sauvaget: HPV vaccination in the developing world11. Patrick Walker, Adeola Atilade, and Henry C. Kitchener: Screening post vaccination12. Richard BS Roden: Second-generation HPV prophylactic vaccines13. Sjored H van der Burg: Therapeutic HPV vaccines14. Peter L. Stern and Henry C. Kitchener: Conclusion