Vascular Cognitive Impairment: Preventable Dementia

Hardcover | May 15, 2003

EditorJohn V. Bowler, Vladimir Hachinski

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Vascular dementia, caused by multiple small strokes, is the second commonest cause of dementia behind Alzheimer's disease. In recent years there has been a radical reappraisal of the concept of vascular dementia and a move away from an Alzheimer-based diagnostic paradigm towards one moreappropriately tailored for vascular disease. Vascular Cognitive Impairment presents a new definition for this class of cerebrovascular process with an emphasis on early detection, prompt treatment and the prevention of disease progression. Vascular Cognitive Impairment: Preventable Dementia presents an overview of the current state of our knowledge in this field. It reviews the historical background, prevalence, risk factors and economic consequences of the condition. In addition, the book summarises our knowledge of thepathological process, describing insight derived from genetic and imaging studies, before examining opportunities for early diagnosis, prevention and the options for management, both now, and as a result of ongoing clinical trials. With contributions from an expert team of international contributors, this book provides a comprehensive summary of the state-of-the-art in this field, providing a framework for a new understanding of a complex, disabling but Preventable condition.

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From the Publisher

Vascular dementia, caused by multiple small strokes, is the second commonest cause of dementia behind Alzheimer's disease. In recent years there has been a radical reappraisal of the concept of vascular dementia and a move away from an Alzheimer-based diagnostic paradigm towards one moreappropriately tailored for vascular disease. Vas...

John Bowler is in the Department of Neurology, Royal Free Hospital, London, UK. Vladimir Hachinski is in the Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, Canada.

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Format:HardcoverDimensions:362 pages, 9.45 × 6.61 × 0.97 inPublished:May 15, 2003Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0192632671

ISBN - 13:9780192632678

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Table of Contents

1. Bowler and Hachinski: Current criteria for vascular dementia: a critical appraisal2. Roman: Historical evolution of the concept of vascular dementia3. Rocca and Knopman: Prevalence and incidence patterns of vascular dementia4. Chui, Mack, Varpetian and Mungas: Evidence-based prognosis of vascular dementia: survival and rate of cognitive decline5. Rockwood, Brown and Fisk: The cost of vascular cognitive impairment6. Munoz: Histopathology7. Sarti and Pantoni: Experimental models of vascular dementia: a focus on white matter disease and incomplete infarction8. Markus: Genetics of vascular dementia9. Rockwood and Shea: Behavioural and psychological symptoms in vascular cognitive impairment10. Desmond: Cognitive patterns11. Ferris: Measurement of cognition12. Sachdev and Looi: Neuropsychological differentiation of Alzheimer's disease and vascular dementia13. Erkinjuntti and Pohjasvaara: Anatomical imaging14. Ward and Brown: Cerebral blood flow and metabolism in vascular dementia15. Sjogren, Blennow and Wallin: Neurochemical markers16. Pantoni: Subtypes of vascular dementia and their pathogenesis: a critical overview17. Scheltens: White matter changes in vascular dementia18. Henon, Pasquier and Leys: Post-stroke dementia19. Futrell: Vasculitis, collagen vascular disease and vascular dementia20. Skoog and Gustafson: Vascular disorders and Alzheimer's disease21. Inzitari, Lamassa and Pantoni: Treatment of vascular dementias22. Marler: Clinical trials in vascular dementia23. Gorelick: Prevention24. Bowler and Hachinski: Vascular cognitive impairment - a new concept

Editorial Reviews

"The book covers in detail all aspects of vascular cognitive impairment from history and current criteria to physiopathology, imaging, and treatment...an excellent review of vascular dementia."--Doody's