Venous Thromboembolism in Advanced Disease: A clinical guide

Paperback | January 4, 2009

EditorSimon I R Noble, Miriam J Johnson, Agnes Y Y Lee

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There is increasing recognition of the burden of venous thromboembolism (VTE) in patients with advanced incurable disease and the clinical, ethical, and philosophical challenges they may pose. With a growing elderly population and oncological therapies helping patients live longer withmalignant disease, VTE is likely to be an ongoing problem. Whilst presentation, diagnosis, and treatment of VTE in general medicine is well established, its management within the palliative care setting is less clear-cut. Clinical presentation is often masked by other palliative symptoms, andsymptoms can be consistent with those of other conditions; diagnosis is therefore underappreciated, and the condition can be difficult to manage.Bringing together contributions from international experts in the field of VTE and palliative care, this book explores the increasing challenges faced by healthcare professionals when managing VTE in advanced disease. Topics such as the epidemiology and pathogenesis of the condition are discussed.It appraises the current evidence informing the prevention, diagnosis, and treatment of VTE, with particular emphasis on its application to patients with incurable malignancy and non-malignant disease. Chapters are illustrated with key learning points and, where appropriate, case studies arepresented to illustrate the decision-making processes that may occur when balancing the evidence with its impact on patient quality of life. This practical resource is invaluable for healthcare professionals working in all areas of medicine where patients with advanced cancer and non-malignant disease are cared for.

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There is increasing recognition of the burden of venous thromboembolism (VTE) in patients with advanced incurable disease and the clinical, ethical, and philosophical challenges they may pose. With a growing elderly population and oncological therapies helping patients live longer withmalignant disease, VTE is likely to be an ongoing p...

Dr Simon Noble is a Clinical Senior Lecturer and Honorary Consultant in Palliative Medicine, Cardiff University and the Royal Gwent Hospital in Wales. His research interests include the management of venous thromboembolism in advanced cancer and the anticancer effects of low molecular weight heparins. He has chaired the APM Task group...

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Format:PaperbackDimensions:192 pages, 9.21 × 6.14 × 0.07 inPublished:January 4, 2009Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199232040

ISBN - 13:9780199232048

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Table of Contents

1. Miriam Johnson and Simon Noble: The challenge for palliative care2. Aneel Ashrani and John A. Heit: Epidemiology of venous thromboembolism3. Sarah J Lewis: Pathogenesis of venous thromboembolism in cancer4. Menno Huisman: Diagnosis of deep-vein thrombosis and pulmonary embolism in cancer patients5. Robert Weinkove and Beverley J Hunt: Anticoagulants: current and future therapeutic options6. Agnes Lee: Treatment and secondary prevention7. Simon Noble: Primary thromboprophylaxis in the advanced cancer patient8. Dawn Dowding and Miriam Johnson: Clinical decision making - treatment of venous thromboembolism (VTE) in patients with advanced cancer9. Sara Booth and Anna Spathis: Venous thromboembolism in non-malignant disease