Viral Proteases And Their Inhibitors by Satya Prakash GuptaViral Proteases And Their Inhibitors by Satya Prakash Gupta

Viral Proteases And Their Inhibitors

bySatya Prakash Gupta

Paperback | July 6, 2017

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Viral Proteases and Their Inhibitorsprovides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.



  • Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition
  • Analyzes structure-activity relationships of inhibitors of each viral protease
  • Presents an in-depth view of the structure and function of viral proteases
Dr. Gupta is one of the pioneers working in theoretical aspects of drug design. He has many excellent publications in highly reputed journals. He has published several reviews in Chemical Reviews and other review periodicals such as Progress in Drug Research, Current Medicinal Chemistry, etc., and contributed many chapters as well as e...
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Title:Viral Proteases And Their InhibitorsFormat:PaperbackDimensions:516 pages, 8.75 × 6.35 × 0.68 inPublished:July 6, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128097124

ISBN - 13:9780128097120

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Table of Contents

1. Fundamentals of Viruses and Their ProteasesAnjana Sharma and Satya P. Gupta

2. Design and Development of Some Viral Protease Inhibitors by QSAR and Molecular Modeling StudiesNoha Saleh Hanan Elhaes and Medhat Ibrahim

3. Advances in Studies on Adenovirus Proteases and Their InhibitorsSatya P. Gupta Basheerulla Shaik and Y. S. Prabhakar

4. Alpha-virus Nonstructural Proteases and Their InhibitorsAkalabya Bissoyi, Subrat KumarPattanayak Arindam Bit Ashish Patel, Abhishek

5. Structure and Function of Alphavirus ProteaseShailly Tomar and Megha Aggarwal

6. Flavivirus Protease: An Antiviral TargetShailly Tomar, Rajat Mudgal and Benazir Fatma

7. Flavivirus NSB/NS3 Protease: Structure, Function, and InhibitionZhong Li Jing Zhang Hongmin Li

8. Design and Development of HCV NS5B Polymerase InhibitorsDebasis Das

9. Studies on HIV-1 Protease and its InhibitorsSonal Dubey

10. Studies on Picornaviral Proteases and Their InhibitorsVaishali M. Patiland Satya P. Gupta

11. Structural Insight into the Viral 3C-like Protease inhibitors: Comparative SAR/QSAR ApproachesNilanjan Adhikari Sandip Kumar Baidya Achintya Saha, Tarun Jha

12. Herpesvirus Proteases: Structure, Function, and InhibitionKriti Kashyap and Rita Kakkar

13. Design and Development of Inhibitors of Herpes Viral Proteases and Their SAR and QSARDimitra Hadjipavlou-Litina and Satya P Gupta

14. Delicate Dance in Treating Hepatitis C Infections and Overcoming ResistanceDolly A. Parasrampuria