Viral Vector Approaches in Neurobiology and Brain Diseases by Riccardo BrambillaViral Vector Approaches in Neurobiology and Brain Diseases by Riccardo Brambilla

Viral Vector Approaches in Neurobiology and Brain Diseases

EditorRiccardo Brambilla

Hardcover | October 16, 2013

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Aiming toward improvement in the safety, efficiency, and specificity of viral vectors for neurobiological research and clinical applications, Viral Vector Approaches in Neurobiology and Brain Diseases covers key aspects related to the use of viral vectors in neuroscience, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain disorders.  The volume begins by delving into features of the viral vectors currently available in neuroscience and their production methods, and it then continues onward to examples of successful applications of viral vector technology to psychiatric and memory research, current applications of viral vector technology in the context of neurological disorders, as well as various cutting-edge applications of viral vector technology to neuroscience, including optogenetics.  Written for the Neuromethods series, the chapters of this book contain the kind of detailed description and implementation advice that promotes successful, repeatable results. Practical and up to date, Viral Vector Approaches in Neurobiology and Brain Diseases will be useful not only to neurobiologists wishing to routinely use viral vectors in the laboratory but also to experienced scientists needing detailed new protocols for a variety of experimental applications.
Title:Viral Vector Approaches in Neurobiology and Brain DiseasesFormat:HardcoverDimensions:345 pagesPublished:October 16, 2013Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1627036091

ISBN - 13:9781627036092

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Table of Contents

Part I: Types of Viral Vectors in Neuroscience Research 1. Lentiviral Vectors as Research Tools in Neurobiology: Design and Production            Alessandro Papale and Riccardo Brambilla 2. Recombinant Adenovirus in Neurobiology            Qian Li and Tong-Chuan He 3. Adeno-Associated Virus-Based Vectors            Nathalie Dutheil and Erwan Bezard 4. Herpes Simplex Virus 1 (HSV-1)-Based Vectors            Aldo Pourchet, Matias E. Melendez, Anna Greco, and Alberto L. Epstein 5. Alphavirus-Based Vectors            Kenneth Lundstrom Part II: Viral Vectors in Memory Research and Psychiatric Diseases 6. Viral Vectors to Study Synaptic Function            Hélène Marie 7. Using Viral Vectors to Study the Memory Trace in Mice            Asim J. Rashid, Chen Yan, and Sheena A. Josselyn 8. Development of Cell-Type Specific Viral Vectors to Tease Apart the Neural Circuitry that Contributes to Drug Addiction            Susan M. Ferguson and John F. Neumaier 9. Using Viral-Mediated Gene Transfer to Study Depressive-Like Behavior            Amy R. Furay and John F. Neumaier Part III: Viral Vectors in Neurological Disorders 10. Gene Therapy for Parkinson's Disease            Erika Elgstrand Wettergren, Luis Quintino, Giuseppe Manfré, and Cecilia Lundberg 11. Lentiviral Vectors in Huntington's Disease Research and Therapy            Aurélie Delzor, Noëlle Dufour, and Nicole Déglon 12. Application of Viral Vectors to Motor Neuron Disorders            Elisabeth Dirren and Bernard L. Schneider Part IV: Applications of Viral Vector Technology to Neuroscience Research 13. In Vivo Gene Silencing by Virally Delivered MicroRNA            Eugenia V. Gurevich, Mohamed R. Ahmed, and Yonatan Carl 14. Viral Manipulation of Neural Stem/Precursor Cells            Nunzio Iraci, Giulia Elisabetta Tyzack, Chiara Cossetti, Clara Alfaro-Cervello, and Stefano Pluchino 15. Viral Vector-Based Techniques for Optogenetic Modulation In Vivo            Mathias Mahn, Shiri Ron, and Ofer Yizhar 16. Viral Vectors for Optogenetics of Hypothalamic Neuropeptides            H. Sophie Knobloch, Alexander Charlet, Ron Stoop, and Valery Grinevich 17. Viral Vectors in Primate Research: Examples from Parkinson's Disease Research            Grégory Porras, Benjamin Dehay, and Erwan Bezard