Vitamin D: Volume 2: Health, Disease And Therapeutics

Hardcover | September 1, 2017

byDavid FeldmanEditorJ. Wesley Pike, Roger Bouillon

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Volume 2: Authoritatively covers the evidence for new roles of vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. This collection represents a "who's who" of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology, and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular disease. Offers a comprehensive reference ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles Chapter authors include the most prominent and well-published names in the field Volume I targets chemistry, metabolism and circulation; mechanisms of action; mineral and bone homeostasis; targets; human physiology; diagnosis and management; nutrition, sunlight, genetics and vitamin D deficiency Volume II presents a clinical focus on disorders; analogs; cancer; immunity, inflammation and disease; and therapeutic applications

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Volume 2: Authoritatively covers the evidence for new roles of vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. This collection represents a "who's who" of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orth...

David Feldman, MD, is Emeritus Professor of Medicine (Active) at Stanford University School of Medicine where he has been on the faculty since 1974. He has been a full professor since 1984 and was chief of the Endocrinology Division for 10 years. His laboratory studies the role of steroid hormone receptors, particularly the vitamin D r...

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Format:HardcoverDimensions:1026 pages, 9.41 × 7.24 × 0.98 inPublished:September 1, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128099631

ISBN - 13:9780128099636

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Table of Contents

Preface David Feldman, J. Wesley Pike, Roger Bouillon, Edward Giovannucci, David Goltzman and Martin Hewison

In Memoriam: Robert P. Heaney, MD (1928-2016) Robert R. Recker and Joan M. Lappe In Memoriam: Milan Uskokovic, PhD (1924-2015) Sylvia Christakos, Hubert Maehr, and Nanjoo Suh

Volume II: Health, Disease and Therapeutics

Section VII. Population Studies: Vitamin D Deficiency, Nutrition, Sunlight, Genes & Trials 58. Methods of evaluating population studies of vitamin D: strengths & weaknesses Edward Giovannucci 59. Worldwide vitamin D status Natasja van Schoor and Paul Lips 60. Vitamin D in Foods: An Evolution of Knowledge Janet M. Roseland, Katherine M. Phillips, Kristine Y. Patterson, Pamela R. Pehrsson, and Christine L. Taylor 61. Determinants of Vitamin D Deficiency from Sun Exposure: A Global Perspective William B. Grant, Harjit Pal Bhattoa, and Pawel Pludowski 62. Vitamin D Fortification and Supplementation Policies to Correct Vitamin D Insufficiency/Deficiency Globally Susan J. Whiting and Mona S. Calvo 63. Vitamin D and Food Fortification Kevin D. Cashman and Mairead Kiely 64. Bariatric Surgery, Vitamin D, and Bone Loss Tiffany Kim, Anne Schafer 65. Genetics of the Vitamin D Endocrine System André G. Uitterlinden 66. Randomized Clinical Trials of Vitamin D for the Primary Prevention of Cancer and Cardiovascular Disease, with a Focus on the VITamin D and OmegA-3 TriaL (VITAL) Shari S. Bassuk, JoAnn E. Manson

Section VIII. Disorders 67. Vitamin D deficiency and nutritional rickets in children John M. Pettifor, Kebashni Thandrayen, and Thomas D. Thacher 68. Vitamin D and Osteoporosis Peter R. Ebeling and John A. Eisman 69. Adult Vitamin D deficiency: fracture & fall prevention Bess Dawson-Hughes and Heike A. Bischoff-Ferrari 70. Clinical Disorders of Phosphate Homeostasis Eva S. Liu and Harald Jüppner 71. Vitamin D hydroxylation-deficient rickets, type 1A: CYP27B1 mutations Francis H. Glorieux, René St-Arnaud 72. Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets Peter J. Malloy, Dov Tiosano and David Feldman 73. The Role of Genetic Variation in CYP2R1, the Principal Vitamin D 25-hydroxylase, in Vitamin D Homeostasis Jeffrey David Roizen and Michael A. Levine 74. Infantile Hypercalcemia and CYP24A1 Mutations Karl P. Schlingmann and Martin Konrad 75. Drug and Hormone Effects on Vitamin D Metabolism Gregory R. Emkey and Sol Epstein 76. Vitamin D and Organ Transplantation Jessica M. Furst, Emily M. Stein, and Elizabeth Shane 77. The role of vitamin D in type 2 diabetes and hypertension Edith Angellotti and Anastassios G. Pittas 78. Vitamin D, obesity and the metabolic syndrome Elina Hypponen and Barbara Boucher 79. Vitamin D and Renal Disease Adriana S. Dusso and Jorge B. Cannata-Andia 80. Calcitriol and Analogs in the Treatment of Chronic Kidney Disease Ishir Bhan and Ravi Thadhani 81. Idiopathic Hypercalciuria and Nephrolithiasis Murray J. Favus, Meltem Zeytinoglu, Fredric L. Coe, 82. Hypercalcemia Due to Vitamin D Toxicity Natalie E. Cusano, Susan Thys-Jacobs, John P. Bilezikian 83. The Hypocalcemic Disorders Rachel I. Gafni, Karl L. Insogna, Thomas O. Carpenter 84. Vitamin D: Cardiovascular Effects and Vascular Calcification Christoph Zechner and Dwight A. Towler 85. Vitamin D and Paget's Disease Noriyoshi Kurihara and David Roodman

Section IX. Vitamin D Analogs 86. Analogs of Calcitriol Lieve Verlinden, Annemieke Verstuyf 87. Non-Secosteroidal Ligands and Modulators of VDR Ryan E. Stites, James G. MacKrell and Keith R. Stayrook 88. Bile acid-derived vitamin D receptor ligands Makoto Makishima and Sachiko Yamada 89. Bifunctional Vitamin D Hybrid Molecules James L. Gleason and John H. White 90. Modulating Vitamin D Receptor-Coregulator Binding with Small Molecules Olivia B. Yu and Leggy A. Arnold 91. Extended-release Calcifediol in Renal Disease Martin Petkovich and Charles W. Bishop 92. Vitamin D Receptor Antagonists Hiroshi Saitoh 93. Eldecalcitol and Osteoporosis Toshio Matsumoto and Fumiaki Takahashi

Section X. Vitamin D and Cancer 94. Overview of vitamin D actions in cancer Marjolein van Driel, Johannes P.T.M. van Leeuwen, Alberto Munoz, and David Feldman 95. Vitamin D Status and Cancer Incidence, Mortality and Prognosis Irene Shui and Edward Giovannucci 96. Effects of Vitamin D Derivatives on Differentiation, Cell Cycle and Apoptosis in Hematological Malignancies George P. Studzinski, Elzbieta Gocek, Frederick Coffman, and Michael Danilenko 97. Vitamin D actions in mammary gland and breast cancer: genomics, metabolism and stem cells Sarah Beaudin and JoEllen Welsh 98. Vitamin D Urologic Cancers Donald Trump 99. Vitamin D and Colon Cancer Antonio Barbáchano, María Jesús Larriba, Gemma Ferrer-Mayorga, José Manuel González-Sancho, Alberto Muñoz 100. Vitamin D and Skin Cancer Katherine J. Ransohoff, Ervin H. Epstein Jr., and Jean Y. Tang 101. Vitamin D and Lung Cancer Tatiana Shaurova, Mukund Seshadri, and Pamela A. Hershberger 102. Vitamin D inflammation and cancer Enikö Kallay and Laura Buburuzan

Section XI. Immunity, Inflammation and Disease 103. Vitamin D and Tuberculosis Adrian R. Martineau, David A. Jolliffe, and Julie Demaret 104. Vitamin D and Adaptive Immunology in Health and Disease Elizabeth H Mann, Paul E. Pfeffer, and Catherine M Hawrylowicz 105. Vitamin D and Innate Immunity Kathryn Zavala, Aria Vazirnia, and Philip T. Liu 106. Vitamin D and Diabetes An-Sofie Vanherwegen, Conny Gysemans, and Chantal Mathieu 107. Vitamin D and Multiple Sclerosis Colleen E. Hayes and Faye E. Nashold 108. Vitamin D and Inflammatory Bowel Disease Margherita T. Cantorna, Danny Bruce 109. Psoriasis and other Skin Diseases Jörg Reichrath and Michael F. Holick

Section XII. Therapeutic Applications and New Advances 110. Sunlight protection by vitamin D compounds Rebecca S. Mason, Mark S. Rybchyn, Katie M. Dixon 111. Vitamin D, Cardiovascular Disease and Hypertension Stefan Pilz 112. Vitamin D, Acute Respiratory Infection, and Asthma/COPD Carlos A. Camargo 113. Vitamin D and Muscle Performance in Athletes Lisa Ceglia and Roberto Toni 114. Vitamin D: Presence and Function in the Eye Jawaher A. Alsalem, Saaeha Rauz, and Graham R. Wallace 115. Adult vitamin D deficiency and adverse brain outcomes Natalie J. Groves, John J. McGrath, and Thomas H. J. Burne 116. Vitamin D in Pregnancy and Lactation: Moving into the Future Bruce W. Hollis and Carol L. Wagner 117. Vitamin D and Critically Ill ICU Patients Kenneth B. Christopher