Vogel and Motulsky's Human Genetics: Problems and Approaches by Michael SpeicherVogel and Motulsky's Human Genetics: Problems and Approaches by Michael Speicher

Vogel and Motulsky's Human Genetics: Problems and Approaches

byMichael SpeicherEditorStylianos E. Antonarakis, Arno G. Motulsky

Hardcover | December 14, 2009

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The ? rst edition of Human Genetics, Problems and Approaches , was published in 1970 by human geneticists Friedrich Vogel and Arno Motulsky as sole authors. The aim was broad coverage and in-depth analysis of both medical and human genetics with an emphasis on problems and approaches with occasional historical c- ments. This point of view was fully explained in an introductory chapter of the three previous editions (1970, 1976, 1997). The book acquired an excellent reputation as an advanced text of human genetics and has been translated into Italian, Japanese, Russian, Chinese, and Portuguese. Our general aims for the fourth edition remain similar and together with novel developments are now set out in the Introduction of this new fourth edition. Around 2004/2005, both Friedrich Vogel and Arno Motulsky, as well as the publishers, felt that the book should be continued with a new fourth edition in the same spirit and coverage as earlier editions, but should now include additional expert authors. After some delay and the death of Friedrich Vogel in the summer of 2006, a new editorial team consisting of Michael R. Speicher of the Medical University of Graz, Austria, Stylianos E. Antonarakis of the University of Geneva Medical School, and Arno G. Motulsky of the University of Washington School of Medicine, was constituted for the fourth edition of the Vogel/Motulsky book in the spirit of the original work.
Title:Vogel and Motulsky's Human Genetics: Problems and ApproachesFormat:HardcoverDimensions:981 pagesPublished:December 14, 2009Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540376534

ISBN - 13:9783540376538

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Table of Contents

IntroductionHistory of Human GeneticsHuman Genome Sequence and VariationChromosomesFrom Genes to Genomics to ProteomicsFormal Genetics of Humans: Modes of Inheritance Linkage Analysis for Monogenic TraitsOligogenic DiseaseFormal Genetics of Humans: Multifactorial Inheritance and Common Diseases Lessons from the Genome-Wide Studies for Complex Multifactorial Disorders and TraitsEpigeneticsHuman Gene Mutation: Mechanisms and ConsequencesHuman HemoglobinHuman Genetics of Infectious DiseasesGene Action: Developmental GeneticsCancer GeneticsThe Role of the Epigenome in Human CancersPopulation Genetic Principles and Human PopulationsConsanguinity, Genetic Drift, and Genetic Diseases in Populations with Reduced Numbers of FoundersHuman EvolutionComparative GenomicsGenetics and Genomics of Human Population StructureGenetic EpidemiologyPharmacogenetics Behavioral GeneticsThe Genetics of PersonalityMental Retardation and Intellectual DisabilityGenetic Factors in Alzheimer Disease and DementiaGenetics of AutismThe Genetics of Alcoholism and Other Addictive DisordersBehavioral Aspects of Chromosomal VariantsGenetics of Schizophrenia and Bipolar Affective DisorderModel Organisms for Human DisordersMouse as a Model for Human DiseaseCaenorhabditis elegans, A Simple Worm: Bridging the Gap Between Traditional And Systems-Level BiologyDrosophila as a Model for Human DiseaseHuman Genetics and the Canine SystemFish as a Model for Human DiseaseGenetic Counseling and Prenatal DiagnosisGene TherapyCloning in Research and Treatment of Human Genetic DiseaseGenetic Medicine and Global HealthGenetic DatabasesDatabases and Genome BrowsersEnsemblGenome BrowserDatabases in Human and Medical GeneticsSubject Index.

Editorial Reviews

"...should be essential reading for all geneticists. Reading the contents alone sparked a sense of anticipation that made this book essential bedtime reading! ... -there's nothing boring here." Heredity"...a classic textbook and compendium of information. It is, therefore, a distinct pleasure to open the third edition..." Trends in GeneticsFrom the reviews of the fourth edition:"A series of high level reviews, produced with the help of 76 co-authors. . There is a welcome emphasis on formal genetics, which sets this book apart from most others. . This is a handsome book, printed on good quality paper, well bound, and generally produced to Springer's customary high standard. . It will presumably mainly end up in libraries . . Anybody needing to prepare a lecture on one of the topics covered would be very glad to find a copy there."­­­ (Andrew Read, Human Genetics, Vol. 128, 2010)