Xenotransplantation: Basic Research and Clinical Applications by Jeffrey L. PlattXenotransplantation: Basic Research and Clinical Applications by Jeffrey L. Platt

Xenotransplantation: Basic Research and Clinical Applications

byJeffrey L. Platt

Paperback | November 5, 2010

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Internationally recognized scientists, clinicians, and technologists review and explain the fundamental molecular and cellular biology that has been applied to the emerging field of transplant immunology and xenotransplantation, and what impact these advances might optimally have on medicine and science. The authoritative experts writing here-many of whom made the basic discoveries underlying the recent advances-examine the biological and immunological hurdles to xenotransplantation, illuminating how the immune system interacts with the xenograft and laying a practical foundation for the use of genetic engineering and animal transplants in the treatment of human disease.
Title:Xenotransplantation: Basic Research and Clinical ApplicationsFormat:PaperbackDimensions:270 pages, 22.9 × 15.2 × 0.01 inPublished:November 5, 2010Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617371270

ISBN - 13:9781617371271

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Table of Contents

Molecular and Cellular Hurdles to XenotransplantationJeffrey L. PlattPathological Responses to XenotransplantationMatilde Bustos and Jeffrey L. PlattNatural Xenoreactive AntibodiesUri GaliliSpecificity of Xenoreactive Natural AntibodiesWilliam Parker, Paul B. Yu, and Yuko C. NakamuraBiophysical Properties of Xenoreactive Natural AntibodiesWilliam Parker, Ryan C. Fields, and Yuko C. NakamuraThe Origin of Xenoreactive Natural AntibodiesPaul B. YuSynthesis of Carbohydrate Antigens Recognized by Xenoreactive AntibodiesMauro S. Sandrin and Ian F. C. McKenzieThe Complement Barrier to XenotransplantationAgustin P. DalmassoDefects and Amplification of Costimulation Across the SpeciesNicola Rogers and Robert LechlerAntibody-Dependent Effects on Cellular ImmunityAntonello Pileggi, R. Damaris Molano, Thierry Berney, and Luca InverardiDisordered Regulation of Coagulation and Platelet Activation in XenotransplantationSimon C. RobsonCurrent Applications of Cellular XenograftsAlbert S. B. EdgeIndex

Editorial Reviews

"This book provides a useful and concise review of the current status of xenotransplantion and introduces the reader to the remaining required developments before effective implementation of xenotransplantation can occur...The editor and authors are recognized authorities in the field of xenotransplantation and this book is an important addition to existing literature on this topic" - Doody's Health Sciences Book Review Journal