Zebrafish by Christiane Nusslein-volhardZebrafish by Christiane Nusslein-volhard


EditorChristiane Nusslein-volhard, Ralf Dahm

Paperback | September 15, 2002

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The zebrafish has become one of the most important model organisms to study biologial processes in vivo. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiologyand disease. The next few years will see the completion of large scale initiatives that exploit the zebrafish as a model system for the understanding of gene function in vertebrates, including the sequencing of the genome. The zebrafish will therefore play an increasingly important role in the future ofbiomedical research. Whole genome sequencing projects, such as the human genome project, have led to the isolation of tens of thousands of genes for which the in vivo function is unknown. It is therefore likely that an increasing number of researchers will turn to organisms such as the zebrafish tounderstand the in vivo requirement for the proteins these genes encode.Recent technical advances now allow the rapid testing of in vivo function of as yet uncharacterised genes in zebrafish in large numbers and at a speed that is impossible in other systems. This book not only provides a complete set of instructions that will allow researchers to establish thezebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.

About The Author

Christiane Nusslein-Volhard and Ralf Dahm are both in the Department of Genetics, Max-Planck-Institut fur Entwicklungsbiologie.
Coming to Life: How Genes Drive Development
Coming to Life: How Genes Drive Development

by Christiane Nusslein-Volhard


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Details & Specs

Title:ZebrafishFormat:PaperbackDimensions:322 pages, 9.69 × 7.44 × 0.74 inPublished:September 15, 2002Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019963808X

ISBN - 13:9780199638086

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Table of Contents

Nusslein-Volhard, Gilmour and Dahm: Introduction1. Brand, Granato and Nusslein-Volhard: Keeping and raising zebrafish2. Schulte-Merker: Looking at embryos3. Schilling: The morphology of larval and adult zebrafish4. Kane and Kiskimoto: Cell labelling and transplantation techniques5. Gilmour, Jessen and Lin: Manipulating gene expression in the zebrafish6. Pelegri: Mutagenesis7. Geisler: Mapping and cloningAppendices1. Dahm: Atlas of embryonic stages of development in the zebrafish2. Frohnhofer: Table of zebrafish mutations