Hans Krebs: Volume 2: Architect of Intermediary Metabolism, 1933-1937

Hardcover | May 1, 1993

byFrederic Lawrence Holmes

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This comprehensive volume completes Frederic Holmes' notable and detailed biography of Hans Krebs, from the investigator's early development through the major phase of his groundbreaking investigation, which lay the foundations upon which the modern structure of intermediary metabolism isbuilt. With access to Krebs' research notebooks as well as to Krebs himself through more than five years of personal interviews, the author provides an insightful analysis of Hans Krebs and of the scientific process as a whole. The first volume, published in 1991, covered Krebs' formative years inGermany, his work with Otto Warburg, and his discovery of the urea cycle in 1932. This second volume reconstructs the investigative pathway and the professional and personal life of Hans Krebs, from the time of his arrival in England in 1933 until 1937, when he made the discovery for which he isbest known--the formulation of the citric acid cycle. Holmes portrays Krebs' activity at the intimate level of daily interactions of thought and action, from which the characteristic patterns of scientific creativity can best be seen. Holmes' fascinating portrait of Krebs integrates the greatscientist's investigative pathways with his personal life. The result is an illuminating analysis of both man and scientist that will be of interest to biochemists and historians of science.

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From the Publisher

This comprehensive volume completes Frederic Holmes' notable and detailed biography of Hans Krebs, from the investigator's early development through the major phase of his groundbreaking investigation, which lay the foundations upon which the modern structure of intermediary metabolism isbuilt. With access to Krebs' research notebooks...

Frederic Lawrence Holmes is at Yale University School of Medicine.
Format:HardcoverDimensions:504 pages, 9.57 × 6.5 × 1.5 inPublished:May 1, 1993Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0195076575

ISBN - 13:9780195076578

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Table of Contents

1. A New Home for a Career2. Laboratory Life in Cambridge3. Progress Under Pressure4. New Moves5. Arrivals and Partings6. The "Great Work"7. Relocations and Dismutations8. Main Routes and Carriers9. Full Circle10. Reflections

Editorial Reviews

"Meticulous and superb scholarship-grounded in laboratory notebooks, correspondence, published scientific papers, biographical materials, and interviews...." --Journal of the History of Biology